Chlorpropamide dosing information -Patients who do not respond completely to 500 mg/day will usually not respond to higher doses. -Total daily dose may be taken as a single dose each morning with breakfast; gastrointestinal intolerance may be relieved by dividing the daily dose.

What are the indications for Chlorpropamide?

DIABINESE (chlorpropamide) is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.

How is Chlorpropamide taken?

Chlorpropamide is usually taken with breakfast or the first main meal of the day. Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

When should acarbose be taken?

It is usually taken three times a day. It is very important to take each dose with the first bite of each main meal. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take acarbose exactly as directed.

When should repaglinide be given?

Repaglinide is usually taken 2 to 4 times daily, within 30 minutes before eating a meal. Follow your doctor's instructions. If you skip a meal, do not take your dose of repaglinide. Wait until your next meal.

Glyburide, Chlorpropamide, and Tolbutamide - Sulfonylureas

25 related questions found

Can I take repaglinide after a meal?

You must take this medication with your meal. You may take it 15 minutes before a meal to 15 minutes after a meal. Many people take it with the first bite of the meal.

Can I take repaglinide with food?

Repaglinide comes as a tablet to take by mouth. The tablets are taken before meals, any time from 30 minutes before a meal to just before the meal. If you skip a meal, you need to skip the dose of repaglinide.

Can I take acarbose after a meal?

Take acarbose at the beginning of a meal. The tablets can be chewed with your first mouthful of food, or swallowed with a drink of water. The most common side-effect is wind (flatulence). Remember to follow any advice you have been given about your diet.

Who should not use acarbose?

Acarbose is not approved for use by anyone younger than 18 years old.

Can you gain weight on acarbose?

After 26 weeks, completed by 37 subjects in the acarbose group and by 38 subjects in the placebo group, a small weight regain of 0.6 kg was documented in the latter, whereas no weight increase was observed under acarbose treatment (p = 0.38, analysis of covariance with initial body weight as covariable).

Does chlorpropamide cause hyponatremia?

Chlorpropamide administration was associated with hyponatremia and serum hypoosmolality, continued sodium excretion despite hyponatremia and an impaired ability to dilute urine maximally and to excrete a water load.

Which of the following drugs cause hypoglycemia when taken with chlorpropamide?

If allopurinol is added to chlorpropamide therapy, patients should be monitored for hypoglycemia. Alogliptin; Metformin: (Moderate) Use of metformin with a sulfonylurea may increase the risk of hypoglycemia. Sulfonylureas are known to cause hypoglycemia.

What is the side effect of chlorpropamide?

Chlorpropamide side effects

severe skin rash, redness, or itching; pale skin, easy bruising or bleeding; fever, chills, sore throat, mouth sores; or. low levels of sodium in the body--headache, confusion, slurred speech, severe weakness, vomiting, loss of coordination, feeling unsteady.

Is chlorpropamide a sulfa drug?

Chlorpropamide - Clinical Pharmacology

While Chlorpropamide is a sulfonamide derivative, it is devoid of antibacterial activity. Chlorpropamide may also prove effective in controlling certain patients who have experienced primary or secondary failure to other sulfonylurea agents.

What is the use of dapsone?

Dapsone is used to treat leprosy and skin infections. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

Why is chlorpropamide used in diabetes insipidus?

Chlorpropamide has been shown to produce an antidiuresis when administered to patients with antidiuretic hormone (ADH)-sensitive diabetes insipidus (DI). The mechanism by which the drug acts has been studied both in patients with DI and in rats with hereditary hypothalamic DI and with a complete deficiency of ADH.

Can you take acarbose and metformin together?

In combination with metformin, acarbose has been shown to improve long-term glycemic control (HbA_1c measurement) by 0.8% (12), 0.65% (18), and 0.9% (19). Acarbose and metformin are both associated with beneficial effects on hyperglycemia, hyperinsulinemia, body weight, and, in some studies, triglyceride levels (20).

Is acarbose the same as metformin?

Previous randomized clinical trials demonstrated that acarbose is as effective as metformin for glycemic control (11–14). Furthermore, in the STOP-NIDDM study, acarbose treatment was shown to prevent 49% of cardiovascular events in patients with impaired glucose tolerance (IGT) (15).

Can acarbose cause anxiety?

Symptoms of low blood sugar include anxiety; behavior change similar to being drunk; blurred vision; cold sweats; confusion; cool, pale skin; difficulty in thinking; drowsiness; excessive hunger; fast heartbeat; headache (continuing); nausea; nervousness; nightmares; restless sleep; shakiness; slurred speech; or ...

Can you take too much acarbose?

The maximum dose is 50 mg taken three times per day with the first bite of each main meal. For people with poor kidney function: If your kidney function decreases below a certain cut-off, your doctor may stop your acarbose and switch you to a more appropriate diabetes medication.

Does acarbose cause bloating?

Common side effects may include: stomach discomfort, gas, bloating; mild diarrhea; or. mild skin rash or itching.

Does acarbose lower blood pressure?

Acarbose treatment significantly attenuated the decrease of postprandial systolic blood pressures from 35.50±12.66 to 22.25±6.90 mmHg (P=0.000), the increase of heart rate from 9.67±5.94 to 5.33±3.20 beats/min (P=0.016), the increase of postprandial blood glucose from 3.55±1.69 to 2.28±1.61 mmol/l (P=0.000), the ...

How fast does repaglinide work?

Repaglinide starts to work in 30 minutes to an hour. Its effect lasts for a few hours. Can repaglinide cause hypoglycemia? Repaglinide can cause low blood sugar (hypoglycemia).

Does repaglinide cause tiredness?

Symptoms may include chills, cold sweat, dizziness, drowsiness, shaking, fast heartbeat, weakness, headache, fainting, tingling of the hands or feet, or hunger. It is a good habit to carry glucose tablets or gel to treat low blood sugar.

How much does repaglinide lower A1c?

When taken just prior to meals, it promotes the release of insulin that normally occurs with meals and is responsible for preventing blood glucose levels from becoming high. It has been shown to lower hemoglobin A1c (HbA1c) levels by 1.6% to 1.9%.